One of the remarkable functions of articular cartilage is its ability to replenish its components in response to the mechanical forces placed on it. Cartilage consists of cells called chrondrocytes which synthesize and deposit around themselves a matrix of giant molecules. This extra-celluar matrix of immense molecules made by chrodrocytes gives cartilage its properties of resilience and tensile strength. The matrix consists of collagen and proteoglycans Collagen, a tough ropy protein that physically connects the tissues, provides the tensile strength of cartilage. Proteoglycans, which consist mainly of hyaluronic acid and glycosaminoglycans (GAGs) are the framework for clooagen to follow. The water-structuring properties of the proteoglycans provide the compressive resilience of cartilage.
In response to increased mechanical forces the constant and ongoing synthesiaing process often generates extremely large demands for building blocks of collagen and proteoglycans with production requirements doubling or tripling over normal amounts. If the raw materials (nutrients) for these building blocks are not available in the amounts required, the synthesizing process is impaired and the cartilage loses its ability to replenish itself. Cosamin provides the raw materials that are essential for the synthesis of synovial fluid and the complete cartilage matrix including collagen, hyluronic acid and the various modified sugar chains of the glycosaminoglycans. Unlike steroids and NSAID’s which can damage chondrocytes, Cosamin in not a drug; it is a true nutraceutical with outstanding safety.